Protein stability: computation, sequence statistics, and new experimental methods
نویسندگان
چکیده
منابع مشابه
Spatial statistics: Methods, models & computation
a Department of Finance & Economics, Texas State University, United States b School of Public Health, University of Minnesota, United States c Institute for Economic Geography and GIScience, Vienna University of Economics and Business Administration, Austria d Centre for Statistics, Queen Mary, University of London, United Kingdom e Department of Geography, Queen Mary, University of London, Uni...
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The Protein Data Bank (PDB) has been a key resource for learning general rules of sequence-structure relationships in proteins. Quantitative insights have been gained by defining geometric descriptors of structure (e.g., distances, dihedral angles, solvent exposure, etc.) and observing their distributions and sequence preferences. Here we argue that as the PDB continues to grow, it may become u...
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ژورنال
عنوان ژورنال: Current Opinion in Structural Biology
سال: 2015
ISSN: 0959-440X
DOI: 10.1016/j.sbi.2015.09.002